It's a throwaway, really. I watched it because it's short and harmless. I didn't mind it, but I'll never need to watch it again.
It's a short-form anime based on an internet radio show, starring its hosts as themselves. Aya Suzaki plays Aya Suzaki, while Asuka Nishi plays Asuka Nishi. Hence the portmanteau title. They also sing its theme song. According to this anime, Suzaki is a cheerfully scatterbrained ginger weirdo, as Nishi explains in detail in ep.2. (Wacky fashion sense, speaks with a fairly thick regional dialect, has unique urination habits, tries to get in the toilet with you, wants to play Cupid, has an eccentric idea of what being sexy means, etc. If nothing else, you have to admire these two actresses' lack of vanity in what kind of public image they're willing to go along with.)
Meanwhile Nishi is the calmer blue-haired one. She's got a goofy family, though.
The show doesn't have a plot. It's just Suzaki and Nishi goofing off together in anime form. They have amusing conversations. It's mildly amusing and I liked Nishi's family, but I mostly stopped having anything to say after the first four episodes. You watch another episode. It's okay. It lasts three and a half minutes. You watch another. The main characters seem like nice people, but there's not a lot of content. I only watched the show this morning and even now I can't remember much about it.
They have the kind of close friendship that allows any kind of conversation. They'll talk about boobs, show their knickers (although not to camera), etc. That's not subtext. It's just the cheerful vulgarity you get between friends. They're also capable of having competitions to see who can go the furthest in weirding someone out (although they'll apologise to their victim afterwards and befriend them). They can also react to potential annoyances (e.g. a noisy person beside them in the cinema) with good-humoured improvised skits that turn the experience into a positive one.
They're likeable. I still wouldn't recommend this anime, though. Even at three and a half minutes, there's not enough there to justify the time it costs to watch it.